- Rosacea Subtype 2 (Bumps and Pimples)
Oracea® is an oral medication that is prescribed for the treatment of rosacea. It reduces the inflammatory lesions (red bumps, blemishes, and pustules) of rosacea, but it does not lessen the facial redness caused by this skin condition.
Anti-inflammatory dose of doxycline
The active ingredient of Oracea® is doxycycline, an antibiotic.
Unlike standard formulations of doxycycline, Oracea® does not work by killing bacteria. Instead, it uses a lower dose, or so-called "anti-inflammatory dose" that is designed to reduce the inflammatory lesions of rosacea.
This difference is important because:
- rosacea is a chronic inflammatory condition — not a bacterial infection
- In many cases, rosacea requires long-term management, and in clinical studies, Oracea® has not shown to contribute to bacterial resistance
What to Expect from Treatment
Many patients treated with Oracea® during clinical trials started to see improvements (reduction in inflammatory lesions) by around 3-4 weeks and these continued through the full 16 week course of the study. In clinical studies, with over 300 patients, 30% were clear of bumps and blemishes by week 16. 50% showed significant improvement over that time.
In this clinical trial, many study subjects demonstrated improvements in their rosacea over course of the study, and approximately 14% were clear or almost clear of rosacea symptoms by the end of the study.
How to Use Oracea®
Oracea® is taken once a day, typically in the morning with a full glass of water. It should be taken at least 1 hour before or 2 hours after a meal.
Take Oracea® exactly as prescribed.
In clinical trials, the most frequent side effects included soreness in the nose and throat (nasopharyngitis), diarrhea and sinus infection. For the most part, the side effects reported were mild in severity. The safety of Oracea® has been studied over nine months, with no increase in side effects seen with longer treatment.
Discuss any concerns you may have with your doctor. Also, be sure to tell your doctor if you:
- Have kidney disease
- Take blood thinners
- Take medicines to treat acne, psoriasis or seizures
- Are pregnant or nursing
- Have had allergic reactions to tetracyclines in the past
There are no equivalent generic medications for ORACEA®, and using more than prescribed will not make it work faster and may lead to additional side effects.
Oracea© is a registered trademark of Galderma Laboratories.
Last updated August 1, 2012.
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